Clinical Research


The University of Nottingham Health Service is an NIHR CRN East Midlands Research Leadership site.

We have over 10 years experience in delivering NHS research, contributing to its future viability and benefiting our patients.

We have a broad portfolio but at the moment we are focused mainly on vaccine and immunity research and studies looking at ways to improve the mental health of younger people.

Priority Covid-19 Vaccine research

Comparing COVID-19 Vaccine Schedule Combinations (Com-COV) Study

We are recruiting people 50 years of age and over to a study of  ‘mixed’ schedules of different COVID-19 vaccines.

There are now a number of vaccines that have been approved to prevent COVID-19 in the UK. These use two-doses, a ‘prime’ first dose, followed by a ‘boost’ second dose some weeks later. The purpose of this trial is to see how well people’s immune systems respond when they are primed with one type of vaccine, then boosted with another and to see how good the response is when the second dose is separated from the first dose by different periods of time.

The trial will take one year to complete per participant (from the time the first dose of vaccine is given)

If you are interested in finding out more, please visit our website: participate-nottingham | Com-CoV (  where you can access the Study Information Booklet and complete a screening questionnaire.

COVID-19 vaccine study (COV002) – Working with the University of Oxford and in partnership with the University of Nottingham, Nottingham University Hospitals NHS Trust (NUH) and NIHR CRN East Midlands we are helping to develop a safe vaccine that can be used to create immunity against the pandemic Coronavirus, and thus prevent Covid-19 disease. But we need your help. Click here to find out more.

Call 111 when you need medical help fast but it’s not a 999 emergencyNHS ChoicesThis site is brought to you by My Surgery Website